Real-time sublimation front advance monitoring system

Sublime

The advance of the sublimation front during primary drying phase in a freeze-drying process is one of the most critical parameters whose control is key to understand the drying kinetics for cycle development and validation as well as to ensure process robustness, repeatability during production cycles and preserve the product critical quality attributes.

Sublime is a new solution developed to overcome the current market needs, as a new PAT tool capable to monitor the advance of the sublimation front temperature interface using single use wireless probes, displaying process product temperature data in real-time, simplifying the introduction and retrieval logistics and reducing the possible risks of cross-contamination.