ABSTRACT
The pharmaceutical industry is increasingly using different sterilization technologies rather than steam sterilization. This increase is driven by the need for sterilizing thermo-labile products or areas that cannot be dimensioned as a pressure vessel (barrier systems such as Closed Restricted Access Areas or Isolators), under “softer” conditions. However, the reliability and repeatability of this process are compromised by the complexity of using a vapor phase compound that requires homogeneity (material, temperature, pressure, moisture), in order to ensure sterility.
